Born in Australia, Mario moved to Paris to study at the Paris American Academy, where he graduated with a Masters in Design and then went on to work at YSL, Balmain, Moschino and later for DKNY.

Having lived and worked around the globe, in 2009 he founded his own company, Arena International, a strategic design and trend studio where he consulted for brands such as Celine and luxury conglomerates such as LVMH. In 2015, Mario launched his own label, ENLIST.

Mario joined Kering in 2018 and worked on Christopher Kane as Head of Ready-to-wear and in 2019 he moved to Nanushka where he was appointed Director of Design and Innovations (Ready-to-wear and Accessories). In 2023, Mario took on the role of Director of Product and Design (Ready-to-wear, Accessories and Runway) at JW Anderson.

Mario was appointed Creative Director for JOSEPH in August 2024.